HdcB, a novel enzyme catalysing maturation of pyruvoyl-dependent histidine decarboxylase
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چکیده
منابع مشابه
HdcB, a novel enzyme catalysing maturation of pyruvoyl-dependent histidine decarboxylase.
Pyruvoyl-dependent histidine decarboxylases are produced as proenzymes that mature by cleavage followed by formation of the pyruvoyl prosthetic group. The histidine decarboxylation pathway of Streptococcus thermophilus CHCC1524 that consists of the pyruvoyl-dependent histidine decarboxylase HdcA and the histidine/histamine exchanger HdcP was functionally expressed in Lactococcus lactis. The ope...
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Molecular modeling analysis of charge density and heat of fornation by PM3 method as well as C, H NMR and 2D-NMR measurements of histidine (substrate) and some of its derivatives as histidine decarboxylase inhibitors were performed. It was established that the atom, usually nitrogen, which forms internal aldimine with pyridoxal5 -phosphate (PLP), (coenzyme), has negative and almost equal ...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2011
ISSN: 0950-382X
DOI: 10.1111/j.1365-2958.2010.07492.x